Medical oncologist graduated from the Université Libre de Bruxelles, 1990, trained at Brussels Institut Jules Bordet Cancer Center, research fellow Lombardi Cancer Center, Georgetown University from 1993-95. In 2014, PhD thesis on Hypoxic stress regulated NK cell immune response at University Paris Sud. In 2003 founded the Laboratory of Experimental Cancer Research at Luxembourg Institute of Health (LIH) and holds currently the position of Associate Medical Director of LIH. Clinical position Staff Oncologist at Centre Hospitalier in Luxembourg where he is currently also Director of Research. Clinical work lung cancer and neurooncology.

Hon Professor of Oncology at University of Luxembourg where he heads the Medical Oncology training program. President of Luxembourg National Institute of Cancer, Luxembourg from 2015 to present and the Society of Oncology from 2013 to 2019 and Médecins sans Frontières Luxembourg from 2015 to 2022. Luxembourg CAT alternate delegate at EMA since 2013 to present.

He is Author or co-author of more than 120 peer reviewed publications and has contributed texts for medical and scientific textbooks in his field.