Dr. Jänne received his MD and PhD from the University of Pennsylvania in 1996. He completed postgraduate training in internal medicine at Brigham and Women’s Hospital and in medical oncology at DFCI in 2001.

He is the director of the Lowe Center for Thoraic Oncology and the Scientific Director, Belfer Institute for Applied Cancer Science. His main research interests include studying the therapeutic relevance of oncogenic alterations in lung cancer.

He was one of the co-discoverers of epidermal growth factor receptor (EGFR) mutations and has led the development of therapeutic strategies for patients with EGFR mutant lung cancer.